RC Strasbourg host AS Monaco at the Stade de la Meinau in a Coupe de France last-16 clash on Thursday evening. The Alsatians enter as underdogs despite their impressive home form this season, with Monaco's European pedigree and squad depth giving them the edge on paper. Gary O'Neil has revitalized Strasbourg since his January arrival, while Sébastien Pocognoli's Monaco side balances domestic cup ambitions with Champions League knockout preparations.
Strasbourg arrive in excellent form under their new English manager. O'Neil oversaw a stunning 4-1 victory at Lille on January 25, preceded by a 2-1 home win against Metz and a 6-0 demolition of Avranches in the previous Coupe de France round. The home side has scored 25 goals in 16 Ligue 1 matches this season, sitting seventh in the table. Emanuel Emegha remains sidelined with a thigh injury, but Dilane Bakwa and Andrey Santos have stepped up with crucial contributions. Strasbourg's attacking approach under O'Neil creates chances at both ends, with 20 goals conceded reflecting their aggressive style.
Monaco's domestic form stands in stark contrast to their European progress. Three Ligue 1 defeats in January—including losses to Lyon and Lorient—have raised concerns, though they did qualify for the Champions League playoffs with a draw against Juventus. Pocognoli faces a defensive crisis with Mohammed Salisu, Wout Faes, and Eric Dier all unavailable, leaving just one fit natural centre-back. The absences of Paul Pogba and Takumi Minamino further stretch squad resources during a demanding schedule. Breel Embolo and Maghnes Akliouche carry the attacking burden, but creating consistency has proved difficult.
Monaco holds the historical advantage with 18 wins to Strasbourg's 8 across their meetings. The Principality club won 3-2 at home in August's league fixture and claimed a 3-1 victory in Strasbourg last November. However, these sides played to a goalless draw in April 2025, and Strasbourg's recent goal-scoring form suggests this encounter will differ from recent meetings. Monaco's injury-depleted defense faces a confident home attack determined to reach the quarter-finals.
I'm backing Both Teams To Score at 1.53. Strasbourg have scored in 14 of their 16 Ligue 1 matches while Monaco conceded in four of their last five away fixtures. The hosts' 1.96 xG projection against Monaco's makeshift defense supports home goals, and Monaco's quality attackers should breach a Strasbourg side that ships goals regularly. The xG projection (1.96–1.30) supports a 2-1 finish.

